Research

Clinical Outcomes in Hip and Knee Arthroplasty

Advancing Quality, Safety, and Durability in Joint Replacement

Dr. Arshi’s clinical outcomes research spans the full spectrum of hip and knee arthroplasty, examining how patient factors, implant design, fixation method, surgical technique, and healthcare setting influence postoperative results.

His work integrates registry analyses, multicenter collaborations, and population-based studies to guide evidence-based practice, improve patient counseling, and advance value-based orthopaedic care.

Research Focus and Key Themes

Dr. Arshi’s research explores the optimization of hip and knee arthroplasty outcomes across diverse patient populations. His work emphasizes:

• Perioperative optimization and outpatient pathways: Population-based studies assessing safety and complication rates for outpatient arthroplasty, risk stratification, and enhanced recovery protocols.
• Risk prediction and patient selection: Development and validation of models to anticipate perioperative complications and functional recovery after joint replacement.
• Socioeconomic and demographic influences: Analyses of how community distress and access to care influence patient outcomes.
• Fixation methods and implant design: Comparative studies of cemented versus cementless fixation, including registry analyses of early outcomes and revision risk.
• Surgical technique and decision making: Development and evaluation of specific surgical techniques in determining patient outcomes.
• Spinal pathology and hip-spine relationships: Understanding how preexisting lumbar fusion and sagittal imbalance affect hip arthroplasty function, stability, and patient-reported outcomes.

Dr. Arshi’s research is broadly read and helps inform modern best practices in surgical planning, patient counseling, and system-level improvement for arthroplasty care.

Representative Publications

1. Schaffler BC, Zaniletti I, Arshi A, De M, Schwarzkopf R, Rozell JC.
   Risk of Early Manipulation in Cemented Versus Cementless Total Knee Arthroplasty: An Analysis of the American Joint Replacement Registry.
   J Arthroplasty. 2025; 40(10): 2510–2517. PMID: 40209822
2. Bloom DA, Bieganowski T, Robin JX, Arshi A, Schwarzkopf R, Rozell JC.
   Evaluation of Preoperative Variables that Improve the Predictive Accuracy of the Risk Assessment and Prediction Tool in Primary Total Hip Arthroplasty.
   J Am Acad Orthop Surg. 2024; 32(22): 1025–1031. PMID: 38754131
3. Schaffler BC, Robin JX, Katzman JL, Arshi A, Rozell JC, Schwarzkopf R.
   Aseptic Tibial Loosening Is Associated With Thickness of the Cement: A Radiographic Case-Control Study.
   J Arthroplasty. 2024; [Epub ahead of print]. PMID: 39710212
4. Khan IA, Cozzarelli NF, Sutton R, Ciesielka KA, Arshi A, Fillingham YA.
   Patients Requiring Both Total Hip Arthroplasty and Lumbar Spinal Fusion Have Lower Hip Functional Outcome Scores: A Matched Case-Control Study.
   J Arthroplasty. 2023. PMID: 37952736
5. Lawrence KW, Raymond HE, Sicat CS, Roof MA, Arshi A, Rozell JC, Schwarzkopf R.
   Indications, Clinical Outcomes, and Re-Revisions Following Revision Total Hip Arthroplasty – Does Age Matter?
   J Arthroplasty. 2023. PMID: 37879423
6. Khan IA, Sutton R, Cozzarelli NF, Ciesielka KA, Parvizi J, Arshi A, Fillingham YA.
   Patients Who Have Had Three or More Levels Fused During Lumbar Spinal Fusion Have Worse Functional Outcomes After Total Hip Arthroplasty.
   J Arthroplasty. 2023. PMID: 36893994
7. McPherson EJ, Sherif SM, DiPane MV, Arshi A.
   Patellar Rebar Augmentation in Revision Total Knee Arthroplasty.
   J Arthroplasty. 2021; 36(2): 670–675. PMID: 32951925
8. Arshi A, Leong NL, Wang JC, Buser Z, Wang J, SooHoo NF.
   Outpatient Total Hip Arthroplasty in the United States: A Population-based Comparative Analysis of Complication Rates.
   J Am Acad Orthop Surg. 2019; 27(2): 61–67. PMID: 30247308
9. Hegde V, Arshi A, Wang C, Buser Z, Wang JC, Jensen AR, Adams JS, Zeegen EN, Bernthal NM.
   Preoperative Vitamin D Deficiency Is Associated With Higher Postoperative Complication Rates in Total Knee Arthroplasty.
   Orthopedics. 2018; 41(4): e489–e495. PMID: 29708568
10. Arshi A, Leong NL, D’Oro A, Wang C, Buser Z, Wang JC, Jones KJ, Petrigliano FA, SooHoo NF.
    Outpatient Total Knee Arthroplasty Is Associated With Higher Risk of Perioperative Complications.
    J Bone Joint Surg Am. 2017; 99(23): 1978–1986. PMID: 29206787

Journals Featuring Dr. Arshi’s Work

• Journal of Arthroplasty
• Journal of Bone and Joint Surgery
• Journal of the American Academy of Orthopaedic Surgeons
• Orthopedics
• Clinical Orthopaedics and Related Research
• Arthroplasty Today

Clinical Impact

Through this body of work, Dr. Arshi continues to advance understanding of surgical quality, equitable outcomes, and patient safety in hip and knee arthroplasty. His research directly informs clinical decision-making for implant selection, perioperative planning, and long-term surveillance strategies across diverse patient populations.

Full Publication List

For a complete and up-to-date list of Dr. Arshi’s publications, please visit his PubMed profile here.

Explore More Research

Dr. Arshi’s work on return to sport is just one aspect of his broader research portfolio in hip and knee replacement surgery.
Explore all research focus areas