Research

Clinical Practice Guidelines in Orthopaedics

Translating Evidence into Safer, Standardized Orthopaedic Care

Clinical practice guidelines serve as the foundation for evidence-based orthopaedic surgery. They help ensure consistent, high-quality care across institutions and patient populations.

Dr. Arshi has contributed to both national and institutional guideline development initiatives, helping to establish best practices for venous thromboembolism (VTE) prevention and periprosthetic joint infection (PJI) management following total joint arthroplasty.

His work bridges clinical research, multidisciplinary consensus, and real-world implementation—translating the best available evidence into actionable recommendations that improve patient outcomes and safety.

Research Focus and Key Themes

• Venous thromboembolism (VTE) prevention: Developing standardized recommendations for pharmacologic and mechanical prophylaxis following hip and knee replacement.
• Periprosthetic joint infection (PJI) diagnosis and management: Establishing evidence-based pathways for infection prevention, early diagnosis, and treatment.
• Institutional protocol development: Authoring NYU’s clinical practice guidelines for both VTE and PJI, integrating national consensus with institutional best practices.
• Evidence synthesis and consensus: Contributing to the International Consensus Meeting (ICM) working groups to define global standards of care.

Representative Publications

1. Cooper AM, Munhoz Lima AL, Luo TD, Arshi A, Spangehl MJ, Elganzoury I, Javad Mortazavi SM, et al.
   2025 ICM: Antibiotic Prophylaxis in Primary Joint Arthroplasty. J Arthroplasty.
   2025. [E-pub ahead of print]. PMID: 41161514
2. ICM-VTE Hip & Knee Delegates.
   Recommendations from the ICM-VTE: Hip & Knee.
   J Bone Joint Surg Am. 2022; 104 (Suppl 1): 180–231. PMID: 35315610
3. ICM-VTE General Delegates.
   Recommendations from the ICM-VTE: General.
   J Bone Joint Surg Am. 2022; 104 (Suppl 1): 4–162. PMID: 35315607
4. Arshi A, Rozell JC, Aggarwal VK, Schwarzkopf R.
   NYU Clinical Practice Guidelines for VTE Prophylaxis: Hip and Knee Arthroplasty.
   Bull Hosp Jt Dis (2013). 2024; 82(2): 103–105. PMID: 38739656
5. Arshi A, Pham VP, Rozell JC, Aggarwal VK, Schwarzkopf R.
   NYU Clinical Practice Guidelines for Periprosthetic Joint Infection: Diagnosis and Treatment.
   Bull Hosp Jt Dis (2013). 2023; 81(2): 151–155. PMID: 37200334

Translational Impact

Dr. Arshi’s work in guideline development helps define modern standards in arthroplasty care—ensuring that prevention, diagnosis, and management strategies are both evidence-based and widely implementable.
These efforts improve consistency of care, reduce complications such as VTE and infection, and enhance overall patient safety across diverse clinical settings.

By uniting multidisciplinary experts and synthesizing best available evidence, Dr. Arshi’s contributions continue to shape national and institutional frameworks for safe, high-value orthopaedic practice.

Full Publication List

For a complete and up-to-date list of Dr. Arshi’s publications, please visit his PubMed profile here.

Explore More Research

Dr. Arshi’s work on return to sport is just one aspect of his broader research portfolio in hip and knee replacement surgery.
Explore all research focus areas